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Innovations in liver transplantation in 2020, position of the Belgian Liver Intestine Advisory Committee (BeLIAC)

Journal Volume 84 - 2021
Issue Fasc.2 - Expert Point of View
Author(s) G. Dahlqvist 1 2, C. Moreno 3, P. Starkel 2, O. Detry 4, L. Coubeau 1, I. Jochmans 5
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PAGES 347-359
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DOI10.51821/84.2.347
Affiliations:
(1) Liver Transplant Unit; Cliniques Universitaires Saint-Luc, Brussels, Belgium
(2) Hepatogastroenterology unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium
(3) Liver Unit, Hopital Universitaire Erasme, Brussels, Belgium
(4) Liver Transplant Unit, Hopital Universitaire du Sart Tilman, Liège, Belgium
(5) Lab of Abdominal Transplantation, Transplantation Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium

Liver transplantation (LT) remains the only curative option for patients suffering from end-stage liver disease, acute liver failure and selected hepatocellular carcinomas and access to the LT-waiting list is limited to certain strict indications. However, LT has shown survival advantages for patients in certain indications such as acute alcoholic hepatitis, hepatocellular carcinoma outside Milan criteria and colorectal cancer metastases. These newer indications increase the pressure in an already difficult context of organ shortage. Strategies to increase the transplantable organ pool are therefore needed. We will discuss here the use of HCV positive grafts as the use of normothermic isolated liver perfusion. Belgian Liver Intestine Advisory Committee (BeLIAC) from the Belgian Transplant Society (BTS) aims to guarantee the balance between the new indications and the available resources.

Keywords: Liver transplantation, HCC, HCV, Alcoholic hepatitis, colorectal cancer metastasis, machine perfusion.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 34217187